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KMID : 0360419670030010015
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Korean Journal of Pharmacology
1967 Volume.3 No. 1 p.15 ~ p.18
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Blood Pressure Response of Chickens to Sympathetic Ganglionic Stimulants
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Abstract
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Sympathetic ganglionic stimulants (DMpp, Wy-615, TMA and McN-A-343) produced pressor response in chickens anesthetized with phenobarbital sodium. In adrenalectomized chickens the pressor activity of DMPP, Wy-615 and TMA was less than in normal chickens, but that of McN-A-343 was unchanged, Hexamethonium (20 mg/kg) and chlorisondamine (5 mg/kg), ganglionic blocking agents, reduced the pressor response to DMPP and Wy-615 but did not abolish the response. The Pressor effect of McN-A-343 was not potentiated by the ganglionic blocking agents, but abolished by atropine.
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